Day 1 :
Keynote Forum
Rajesh Sunasee
State University of New York at Plattsburgh, USA
Keynote: Design of cellulose nanocrystals-based functional biomaterials for innovative applications
Time : 08:40-09:40
Biography:
Rajesh Sunasee completed his PhD in Organic Chemistry in 2009 from the University of Alberta in Canada and was the recipient of an NSERC-IRDF Industrial Postdoctoral Scholarship at Omegachem Inc., Quebec, Canada. He is currently an Associate Professor of Chemistry at SUNY Plattsburgh. His research focuses on surface modifications of cellulose nanocrystals for potential biomedical applications and has published 20 peer-reviewed papers, 3 book chapters, and 1 encyclopedia chapter. He was recently the recipient of SUNY Chancellor’s Award for Excellence in Teaching. He continues to serve as an Alternate Councilor for the Northern New York American Chemical Society local chapter.
Abstract:
Research on cellulose nanocrystals (CNCs) continues to garner a high level of attention in both academia and industrial sectors due to their unique physicochemical properties. Their large surface area, excellent mechanical properties, biocompatibility, renewability, biodegradability and the presence of ample hydroxyl groups for surface chemical modifications have rendered them as attractive bionanomaterials for a number of innovative applications. CNCs can be easily derived via the acidic hydrolysis of native cellulose, the latter being the world most ubiquitous and abundant biopolymers. Depending on the source and extraction procedures, the resulting rod-like CNCs possess a nanoscale dimensions ranging from 50 to 3000nm in length with the cross-sections of 3-20nm. This talk will highlight the use of CNCs in various applications with the main focus on surface chemical modifications of CNCs. Surface chemical modifications of CNCs is an important process as it needs to be done in a such a way it does not affect the morphology and structural integrity of CNCs. Different fabrication strategies will be discussed for the design of CNC-based functional advanced biomaterials.
Keynote Forum
Ting Guo
University of California-Davis, USA
Keynote: X-ray nanochemistry: Concepts and development
Time : 09:40-10:40
Biography:
Ting Guo has completed his PhD from the Department of Chemistry at Rice University and postdoctoral training from the Department of Chemistry at the University of California, San Diego. He joined the faculty of the Department of Chemistry at University of California, Davis in 1999, and served as the chair of the department from 2016 to 2018. He has published nearly 100 papers and recently a book on X-ray nanochemistry (Springer International Publishing).
Abstract:
X-ray nanochemistry is a new discipline that has been researched for nearly two decades. It is formally named in 2012. X-ray nanochemistry studies how to use nanomaterials to increase the effectiveness of X-ray radiation. An example is to use an X-ray scintillating nanoparticles to absorb X-rays and emit UV-Vis photons and then use dye molecules to resonantly absorb the photons and generate reactive oxygen species. Another example is to use gold nanoparticles as catalysts to increase the conversion efficiency of radical intermediates produced by X-ray irradiation. In this talk, the overall field of X-ray nanochemistry is reviewed, including basic concepts and applications, which include catalysis, biology, and medicine.
Keynote Forum
Tetsuya Suzuki
Keio University, Japan
Keynote: Carbon and SiOCH films synthesized by atmospheric pressure method
Time : 11:00-12:00
Biography:
Tetsuya Suzuki works as a Professor in Center for Environment and Energy, Keio University. In 1985: Graduated from Inorganic Materials department of Tokyo Institute of Technology, 1990: PhD from Department of Nuclear Engineering, Tokyo Institute of Technology, 2005: Professor, Center for Environment and Energy, Keio University, 2013-2018: Director of Keio Leading-Edge Laboratory.
Abstract:
There are many reports on diamond-like carbon (DLC) films by the atmospheric pressure chemical vapor deposition (AP-CVD) in order to improve their hardness, but it did not succeed because the dense plasma reacts each other in the space and forms particles before arriving onto the substrates. In 2014, our group succeeded in synthesizing hard a-C:H films by the filamentary dielectric barrier discharge (FDBD). In the filament-shaped plasma, the ion density is much larger than that of glow discharge, results in forming larger sp3 bonding. In this study, the discharge type was transited from glow DBD (GDBD) to FDBD by increasing the gap between the electrodes from 1mm to 4mm. The hydrogen concentration of the a-C:H films synthesized by FDBD was reduced compared to that of the films synthesized by GDBD. The hardness of the films increased from 4GPa to 12GPa. These results show that the hard a-C:H films can be synthesized even at low temperature by FDBD. In this study, we also set up a remote-type plasma enhanced CVD apparatus and synthesized SiOCH films under atmospheric pressure. The hardness of the SiOCH increased from 0.5GPa to 2.5GPa as the oxygen flow rate increased from 0ml/min to 750ml/min. The remote-type methods on SiOCH films are suitable for coating on curve surface such as car windows of polycarbonate.
- Nanochemistry | Nano Pharmaceutical Chemistry | Nanochemistry Applications | Organic Materials in Nanochemistry | Nano-Electromechanically Systems | Nano Membranes | Nano Structural Materials | Nanophotonic Materials | Application and Commercialization of Nanotechnology
Location: San Francisco, USA
Chair
Rajesh Sunasee
State University of New York, USA
Co-Chair
Tetsuya Suzuki
Keio University, Japan
Session Introduction
Byung Kim
University of Massachusetts Amherst, USA
Title: Detection of pancreatic cancer biomarkers using a SERS-based immunoassay using gold nanoparticles and nanoshells
Biography:
Byung Kim is a Professor in the Department of Mechanical and Industrial Engineering at the University of Massachusetts in Amherst. His current research interests are micro/nano embossing and its application to obtain a cost-effective solution in the areas such as cancer detecting SERS substrate. He is on the editorial board of the Polymer-Plastics Technology and Engineering Journal. His professional affiliations include membership with the SPE, ASME, SME. He received his BS in Mechanical Engineering from the University of California at Berkeley in 1978 and MS and PhD from MIT in 1980 and 1983, respectively.
Abstract:
Early diagnosis of pancreatic cancer (PC) is critical to reducing the mortality rate of this disease. Current biological analysis approaches cannot robustly detect several low abundance PC biomarkers in sera, limiting the clinical application of these biomarkers. Enzyme-linked immunosorbent assay and radioimmunoassay are two common platforms for detection of biomarkers; however, they suffer from some limitations. This presentation investigates a novel system for multiplex detection of pancreatic biomarkers CA19-9, MMP7, Mesothelin and MUC4 in sera samples with high sensitivity using surface-enhanced Raman spectroscopy. The gold nanoshell showed better Raman intensity compared to that of the gold nanoparticles. Measuring the Raman signals of these biomarkers in PC patients, pancreatitis patients, and healthy individuals reveal the unique expression pattern of these markers in PC patients, suggesting the great potential of using this approach for early diagnostics of PCs. Advantages and feasibility of performing this platform on an integrated microfluidic device also will be discussed.
Preeti Singla
Panjab University, India
Title: Boron nitride nanomaterials: An effective and upcoming approach for water purification
Biography:
Preeti Singla has completed PhD last year in the field of Nano-chemistry and Theoretical chemistry from the department of chemistry, Panjab University, Chandigarh, India. Recently, looking forward to the postdoctoral studies in the USA. Her research is focused on the synthesis, characterization, and application of nanomaterials both experimentally and theoretically. She had published 10 papers in peer-reviewed journals.
Abstract:
Organic pollutants in the aquatic systems are the emerging class of contaminants owing to their prevalence and high stability. In this regard, promising nanomaterial i.e. boron nitride (BN) nanomaterials have been fabricated by adopting solid-state high-temperature annealing methods, characterized using various techniques including Fourier transform infrared spectroscopy, X-ray diffraction technique and high-resolution transmission electron microscopy and then explored towards the adsorption applications. To elucidate their brilliant adsorbent properties, a variety of toxic organic pollutants consisting dyes and pharmaceutical wastage have been taken into consideration as adsorbates. In the present study, critical investigation on the adsorption of fluoroquinolone antibiotic over the surface of BN nanomaterials has been carried out. Effect of various experimental parameters on the extent of adsorption such as contact time, pH, adsorbent dosage and initial antibiotic concentration has also been explored. Furthermore, to demonstrate the nature of adsorption, adsorption isotherm; Langmuir and Freundlich's isotherms have also been studied. Subsequently, the kinetic analysis including the calculation of rate constant has also been accomplished by incorporating the kinetic models. Results obtained from this work demonstrated that BN nanomaterials are very efficacious adsorbents for the removal of antibiotics from water and might also be used in drug delivery systems.
Arjun Sharmah
University of California-Davis, USA
Title: X-ray induced energy transfer in nanoscale materials under X-ray irradiation: Experimental and theoretical studies
Biography:
Arjun Sharmah completed his PhD from the Department of Chemistry at University of California-Davis in 2016 and is currently a postdoctoral researcher postdoctoral at the same institution working in the field of nanochemistry and nanosensor development for drought sensing in plants.
Abstract:
A nanoscale probe of calcium phosphate enclosed liposomes filled with sulforhodamine B (SRB) aqueous solution was synthesized, and the degradation of SRB in the probes was used to measure the enhanced energy deposition within the nanoscale probes mixed with PEGylated gold nanoparticles under X-ray irradiation. The enhancement was measured as a function of the gold nanoparticle concentration, and the results showed a jump at 0.46nM of gold nanoparticles with a slope of 42-fold per one weight percentage (wp–1) of gold in water superimposed on a gentle 1-fold wp–1 slope. Theoretical simulations revealed that the jump was caused by the previously proposed type 2 physical enhancement (T2PE) exerted from a single 90nm gold nanoparticle on a contacting nanoscale probe, and the gentler slope by type 1 physical enhancement (T1PE) was caused by the rest of the gold nanoparticles hundreds of nanometers or farther away. The jump is equivalent to a 2-fold absolute enhancement for each nanoscale probe and suggests that T1PE and T2PE obey the addition algorithm. A systematic theoretical study was also carried out to investigate XIET between a strongly X-ray absorbing gold nanoparticles (donors) and a weakly X-ray absorbing hollow silica nanoparticle filled with water (acceptor), where part of the energy absorbed by the donors can be transferred to the acceptor when the two are positioned sufficiently close to each other and under 20–100keV X-ray irradiation. XIET was studied as a function of dimension, composition, configuration and orientation of donors and acceptors, number of donors, and X-ray energy. These results provide a theoretical framework to guide future experimental XIET studies.
Sujan Kasani
West Virginia University, USA
Title: Tunable localized surface plasmon resonance in transition metal oxide nanostructures
Biography:
Sujan Kasani is currently a PhD student of Electrical Engineering department in West Virginia University, USA. His research area cover nanofabrication, semiconductor electronics, biosensors, and solar energy. He published (first and co-authored) 8 papers in high impact factor journals which include Nano Research, JPCC, Analytical Chemistry, and Nanoscale Horizons. He is also serving as a reviewer for Elsevier-Photonics and Nanostructures, IOP-Nanotechnology and ISME.
Abstract:
Noble metals in plasmonics have been investigated because of its applications in biosensing, optoelectronic and photonic devices. The high electron density of metals, which allows the plasmon resonance to fall in the visible range and the stable metallic properties allowed metals to be the best candidates for plasmonic applications in spite of the high cost. Recent progress in Transition metal oxides (TMO’s) research exhibits plasmonic behavior in visible and NIR region which is more interesting that noble metals because of cost and stability. In this paper, we have demonstrated tunable LSPR of hydrogen treated molybdenum trioxide and compared thin films with nanostructured MoO3. The electrical and optical properties are characterized and discussed the physics of tunable plasmon in TMO’s.